Smart drug design to prevent malaria treatment resistance
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Biochemistry
May 9, 2019
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For the first time, scientists have revealed the essential genes for the most deadly human malaria parasite, Plasmodium falciparum. Researchers from the Wellcome Sanger Institute and the University of South Florida (USF) ...
Cell & Microbiology
May 3, 2018
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Resistance to malaria drugs means that pregnant women are unable to overcome the anaemia caused by the malaria parasite – and their babies are born undersized. A study carried out at Karolinska Institutet, however, exposes ...
Cell & Microbiology
May 9, 2017
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An international group of researchers has proven that a molecule called TCMDC-135051 can selectively inhibit a protein that is essential to the lifecycle of Plasmodium falciparum, one of the parasites that causes malaria.
Cell & Microbiology
Oct 7, 2019
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A University of South Florida College of Public Health professor and his team of researchers have become the first to uncover part of the mysterious process by which malaria-related parasites spread at explosive and deadly ...
Cell & Microbiology
Mar 4, 2015
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Scientists have shed light on how malaria is able to resist treatment with a leading drug.
Biotechnology
Oct 12, 2010
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Malaria remains one of the world's leading causes of mortality in developing countries. Last year alone, it killed more than 400,000 people, mostly young children. This week in ACS Central Science, an international consortium ...
Biochemistry
Sep 14, 2016
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Approximately 350 million to 500 million cases of malaria are diagnosed each year mostly in sub-Saharan Africa. While medications to prevent and treat malaria do exist, the demand for new treatments is on the rise, in part, ...
Biochemistry
May 18, 2009
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An experimental drug, called DSM265, cured seven volunteers of a Plasmodium falciparum infection, a malaria parasite that is a major cause of morbidity and mortality worldwide. The goal of this research is to find a cure ...
Cell & Microbiology
Mar 11, 2019
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Scientists have made a major breakthrough in the global search for a new drug to beat the malaria parasite's growing resistance to first-defence treatments.
Biochemistry
Feb 10, 2016
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