Scientists have discovered that the malaria parasite Plasmodium vivax is evolving rapidly to adapt to conditions in different geographical locations, in particular to defend itself against widely-used antimalarial drugs. ...
Biotechnology
Jun 27, 2016
0
130
For the first time, UBC researchers have shown a key difference in the three-dimensional structures of a key metabolic enzyme in the parasite that causes malaria compared to its human counterpart.
Biochemistry
May 1, 2020
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224
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don't prevent infection or transmission via mosquitoes. What's ...
Cell & Microbiology
Dec 6, 2018
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64
The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.
Cell & Microbiology
Jul 27, 2015
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34
NUS scientists in collaboration with researchers from Norvatis have discovered two genetic markers in Plasmodium falciparum, the deadliest malaria parasite that can cause it to develop resistance against a new antimalarial ...
Cell & Microbiology
Jan 3, 2018
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76
Limiting a much-needed resource could pit pathogens against one another and prevent the emergence of drug resistance. New research demonstrates that harnessing competition among pathogens inside a patient could extend the ...
Cell & Microbiology
Dec 11, 2017
0
115
Maryse Lebrun, Research Director at Inserm, and her fellow researchers at the Laboratoire Dynamique des interactions membranaires normales et pathologiques (CNRS, France), have characterised a protein complex that allows ...
Cell & Microbiology
Jul 25, 2011
0
0
The search for new treatments to combat malaria has been hampered by the lack of validated targets on the parasite that causes the disease. In work recently published in PNAS, a team from the Drug Discovery Unit at the University ...
Analytical Chemistry
Sep 27, 2019
0
21
The iron-containing molecule heme is necessary for life. Cells require heme to perform the chemical reactions that produce energy, among other critical tasks.
Cell & Microbiology
Feb 27, 2017
0
10
Scientists have documented for the first time how competition among different malaria parasite strains in human hosts could influence the spread of drug resistance.
Cell & Microbiology
Mar 22, 2016
0
15
