Solving streptide from structure to biosynthesis

Bacteria speak to one another using peptide signals in a soundless language known as quorum sensing. In a step towards translating bacterial communications, researchers at Princeton University have revealed the structure ...

In slow motion against antibiotic resistance

There are currently only a few synthetic agents that bind to and block the widespread membrane transport proteins, ATP-binding cassette transporters (ABC). Scientists at Goethe University and the University of Tokyo identified ...

Unique organic light-emitting molecular emitters

A team including researchers from Osaka University has produced a new molecular emitter for organic light-emitting diodes (OLEDs). Using rational chemical design with U-shaped synthetic building blocks, the scientists were ...

Learning from nature's bounty: New libraries for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...

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