Macrocycles are molecules made of large rings of atoms. Despite being relatively big and flexible, the molecules don't always stay "floppy"—they can actually lock themselves into specific shapes and geometries.
Materials Science
Feb 21, 2020
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56
A team including researchers from Osaka University has produced a new molecular emitter for organic light-emitting diodes (OLEDs). Using rational chemical design with U-shaped synthetic building blocks, the scientists were ...
Materials Science
Jan 20, 2020
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21
Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study is published in Science ...
Materials Science
Aug 21, 2019
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55
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...
Biochemistry
Jun 11, 2019
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3
Hepatocyte Growth Factor (HGF) is a protein that acts as a cell growth factor. By binding to its receptor protein MET on the cell membrane, it exerts its physiological functions such as proliferation and migration of cells, ...
Biochemistry
May 29, 2019
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9
In biology, folded proteins are responsible for most advanced functions. These complex proteins are the result of evolution or design by scientists. Now, a team of scientists led by University of Groningen Professor of Systems ...
For us humans, a healthy brain handles all the minute details of bodily motion without demanding conscious attention. Not so for brainless robots – in fact, calculating robotic movement is its own scientific subfield.
Biochemistry
Jan 16, 2018
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10
New computational strategies reported this week in Science might help realize the promise of peptide-based drugs. Peptides are similar to protein molecules, but differ in their smaller size, structure and functions.
Biochemistry
Dec 14, 2017
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143
Selective ion transport is the foundation of water purification technology, as well as underpinning a range of biological effects—such as the function of nerves—and diagnostic technologies that use ion-sensitive electrodes ...
Materials Science
Aug 10, 2016
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14
Inspired by the classic 'ball-in-a-cup' children's toy, researchers at the University of York have discovered an innovative method to make medicinally important molecules.
Materials Science
Nov 17, 2015
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16
