Researchers from Osaka University have found that the attachment of a ubiquitin molecule to a protein called PCNA at the lysine 107 position causes gross chromosomal rearrangements. This lysine is located where two PCNA molecules ...
Cell & Microbiology
Jul 22, 2021
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12
A research team led by Prof. Huang Qing from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences has used infrared and Raman spectroscopy to identify lysine acetylation features, providing ...
Biochemistry
Jun 24, 2022
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54
Plants have evolved to produce a variety of compounds that vary from species to species. These compounds play a key role for the survival strategies of plants. Compounds that are bitter and poisonous protect the plants from ...
Plants & Animals
Aug 1, 2019
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7
Intrinsically disordered regions (IDRs) of proteins, when tethered to folded domains, function either as flexible tails or as linkers between domains. Most IDRs are composed of a mixture of oppositely charged residues. Recent ...
Molecular & Computational biology
May 9, 2022
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39
Mussels survive by sticking to rocks in the fierce waves or tides underwater. Materials mimicking this underwater adhesion are widely used for skin or bone adhesion, for modifying the surface of a scaffold, or even in drug ...
Materials Science
Jun 1, 2021
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8
Humans are in a constant arms race with infectious bacteria. To kill these disease microbes, we develop powerful antibiotics; and in turn, the bacteria develop resistance against these drugs. So we enhance our antibiotics, ...
Cell & Microbiology
Feb 4, 2019
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3
Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...
Cell & Microbiology
Jan 24, 2019
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5
In eukaryotes, genomic DNA, which is a very long double helix containing all the genetic information, wraps around a globular protein called a histone and folds it many times before being contained within the nucleus.
Molecular & Computational biology
Sep 22, 2023
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1
Harmful bacteria react less and less to common antibiotics. The infections they cause are therefore increasingly deadly. World health therefore urgently needs alternative antibacterial agents. "Our VersaTile platform gives ...
Cell & Microbiology
Jun 4, 2020
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1
To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study in eLife shows.
Cell & Microbiology
Aug 11, 2020
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