DNA replication under the microscope
Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.
Molecular & Computational biology
Nov 22, 2021
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848
Light-sheet microscopy is one of the most powerful method for imaging the development and function of whole living organisms. However, achieving high-resolution images with these microscopes requires manual adjustments during ...
Biotechnology
Nov 1, 2016
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609
To make it possible for cellular agriculture—the process of growing meat in bioreactors—to feed millions of people, several technical challenges will have to be overcome. Muscle cells from chicken, fish, cows, and other ...
Biotechnology
May 10, 2023
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185
The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide ...
Materials Science
Aug 22, 2019
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246
Cellular mitosis depends in part on small organelles that extend spindles to pull apart chromosome pairs. Before they can perform this and other essential tasks, these tiny cylindrical structures—known as centrioles in ...
Cell & Microbiology
Sep 11, 2015
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842
A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.
Cell & Microbiology
Apr 12, 2024
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68
UC Riverside scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width ...
Plants & Animals
Mar 23, 2023
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62
In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change ...
Biochemistry
Jan 2, 2024
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92
(Phys.org) —A team of researchers working at the Sloan Kettering Institute for Cancer Research has succeeded in building a glycoprotein from scratch. It marks an enormous step forward, the team reports in their paper published ...
Human chromosomes are long polymer chains that store genetic information. The nucleus of each cell contains the entire human genome (DNA) encoded on 46 chromosomes with a total length of about 2 meters. To fit into the microscopic ...
General Physics
Nov 22, 2023
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44