Molecular probe maps misfolded proteome state in live cells

The folding state of the proteins in live cells often reflect the cell's general health. Australian scientists have developed a molecular probe that senses the state of the proteome—the entire set of the proteins—by measuring ...

How bacteria control their cell cycle

Researchers at the Biozentrum of the University of Basel have demonstrated how bacteria coordinate cell division with the replication of their genetic material. In an interdisciplinary study they explain why the current concept ...

The 'airbag' that protects cells against stress

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified the molecular mechanisms that allow cells to survive mechanical stress. The results, published today in Nature Communications, show ...

Designer lens helps see the big picture

Microscopes have been at the center of many of the most important advances in biology for many centuries. Now, KAUST researchers have shown how a standard microscope can be adapted to provide even more information.

Histone modifications are the influencers of zygotic genome awakening

The zebrafish is an important model organism in biology. Humans and zebrafish share 70 percent of their genes, and more than 80 percent of human genes associated with disease are known to have a zebrafish counterpart. Additionally, ...

'Just clicking' a molecule to a biomolecule for another function

Researchers have reported a material that controls the behavior of cells in a dynamic way, just as happens in biology. A new technique uses functional components that can be 'clicked' to a material using vitamin H. Researchers ...

Capturing extreme close-ups of cellular gene expression

Scientists studying genetic transcription are gaining new insights into a process that is fundamental to all life. Transcription is the first step in gene expression, the process taking place within all living cells by which ...

Biomaterials smarten up with CRISPR

The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide ...

page 1 from 23