Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can ...
Cell & Microbiology
Apr 8, 2024
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17
Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA pioneers at the University of Pennsylvania.
Biotechnology
Apr 3, 2024
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6
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...
Bio & Medicine
Apr 3, 2024
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18
For patients with certain types of cancer, CAR T cell therapy has been nothing short of life changing. Developed in part by Carl June, Richard W. Vague Professor at the Perelman School of Medicine, and approved by the Food ...
Bio & Medicine
Mar 25, 2024
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47
Polyolefins are a type of plastic that is resistant to breaking down. This makes this plastic—a kind found in everything from grocery bags to car bumpers—hard to recycle. In a new study, scientists have discovered a potential ...
Biotechnology
Mar 20, 2024
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21
Soda lakes, which are dominated by dissolved sodium and carbonate species, could have provided the right conditions for the first cells, according to a new study published in PNAS Nexus.
Evolution
Mar 20, 2024
0
164
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with ...
Bio & Medicine
Mar 19, 2024
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4
A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University. Thanks to an innovative ...
Biochemistry
Mar 12, 2024
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46
Finding the best method to deliver chemotherapeutic drugs to tumor cells can be tricky. Ideally, the treatments target tumor cells while leaving healthy cells alone.
Bio & Medicine
Mar 12, 2024
0
1
Too often, the lack of clinical trials means that pregnant women suffer because available medications are prescribed off-label for them or not at all. A new study offers proof of concept for the important parameters to develop ...
Bio & Medicine
Mar 8, 2024
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