A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...
Cell & Microbiology
Apr 21, 2022
0
8
Researchers at the Institute for Chemical Reaction Design and Discovery and Hokkaido University have developed a virtual ligand-assisted (VLA) screening method that could drastically reduce the amount of trial and error required ...
Materials Science
Mar 14, 2022
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22
MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple ...
Biochemistry
Feb 18, 2022
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516
Currently, the world's energy demand mainly depends on fossil fuels being a limited resource. The consumption of fossil fuels leads to emission of carbon dioxide (CO2) that is one of the major greenhouse gases contributing ...
Materials Science
Feb 11, 2022
0
121
Apoptosis is a process that causes cell death. It can go awry in cancer cells, sustaining the disease. Scientists at St. Jude Children's Research Hospital have captured the structure of BAK, a protein that triggers apoptosis. ...
Cell & Microbiology
Jan 11, 2022
0
91
Chiral phosphines are one of the most commonly used ligands in assymetric metal catalysis for the synthesis of various useful drugs and pharmaceuticals. Have you ever wondered how to obtain them? Most of the so-called chiral ...
Materials Science
Jan 7, 2022
0
55
Ion channels in the nervous system are among the most important targets for insecticides. Understanding the structure of the channels is key for the identification of novel species-specific binding sites of agrochemicals. ...
Plants & Animals
Dec 14, 2021
0
187
A team of researchers at RWTH Aachen University and the University of Jyväskylä has developed a system based on machine learning and computationally derived descriptors that can be used to find special kinds of catalysts. ...
The process of purifying biopharmaceutical drugs remains a costly and time-consuming challenge. A deeper understanding of how unwanted elements within biomanufactured proteins bind to the molecules developed to remove them ...
Materials Science
Nov 3, 2021
0
131
Portulaca oleracea, a kind of annual herb widely distributed all over the world, is a well-received vegetable and a traditional herbal medicine with plentiful nutrients and manifold pharmacological activities. However, the ...
Biochemistry
Nov 3, 2021
0
24
