In order for tumors to successfully take hold and spread in the body, they typically must meet several developmental milestones. These include things like suppressing apoptosis, cultivating replication and angiogenesis, weaning ...
Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes—parasitic flatworms that cause the little-known tropical disease schistosomiasis. The findings, published ...
Cell & Microbiology
Sep 24, 2020
0
147
Tyrosine phosphorylation (pTyr) can initiate cellular signaling and govern cellular functions. Its dysregulation is implicated in many diseases, especially cancers. Specific detection of pTyr-is important for developing targeted ...
Bio & Medicine
Sep 17, 2020
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6
A team at the Max Dellbruck Center has answered a question that has puzzled scientists for some 40 years. In the journal Cell, the group explains how cells are able to switch on completely different signaling pathways using ...
Cell & Microbiology
Aug 25, 2020
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75
Researchers from Aarhus University challenge one of the cornerstones of biochemistry, the Michaelis-Menten equation. They show that many enzymes in signaling pathways are independent of substrate concentration, because the ...
Biochemistry
Aug 20, 2020
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375
PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how PIM kinases enhance cancer cell motility by regulating ...
Cell & Microbiology
Aug 19, 2020
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5
Cellular signal transmission is not only optimized for precision—it also includes a cost cap. The relationship between information and energy, a concept well established in physics and engineering, is likely to fundamentally ...
Cell & Microbiology
Jul 20, 2020
0
126
A team of researchers affiliated with several institutions in South Korea has found that stimulating production of a certain enzyme in roundworms can increase their lifespan. In their paper published in the journal Science ...
Leiden chemists have developed a new technique with which they can determine the role of kinases—a group of proteins—in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer ...
Biotechnology
Jun 29, 2020
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21
A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
0
3
