Spotting a molecular warhead for disease in the human gut
Yale scientists are using new chemical tools to identify and understand molecules in the human gut that alter DNA and regulate inflammatory bowel diseases and colorectal cancers.
Yale scientists are using new chemical tools to identify and understand molecules in the human gut that alter DNA and regulate inflammatory bowel diseases and colorectal cancers.
Biochemistry
Apr 7, 2015
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Inflammatory bowel diseases (IBDs), including Crohn disease and ulcerative colitis, are hard to completely cure. Globally, IBDs affect more than 4 million people, today. However, Professor Soichi Tanabe (Graduate School of ...
Biochemistry
Feb 18, 2015
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(Phys.org) —University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn's disease. ...
Biochemistry
Jul 17, 2014
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An international team, composed of 11 institutions from six countries, including BGI, presented the whole-genome sequence of Trichuris suis, a parasitic worm in pig. Understanding the genetics mechanisms underlying the pig ...
Biotechnology
Jun 20, 2014
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(Phys.org) —Much like how a snowplow is needed to clear streets of heavy snow, cells employ a set of genes to clear away misfolded proteins, to prevent them from accumulating and destroying the cell.
Cell & Microbiology
Jan 24, 2014
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Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters the body through the ...
Biotechnology
Jan 19, 2014
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Scientists from the Emory University School of Medicine in Atlanta, United States have shown that specific gut bacteria are beneficial for maintaining a healthy intestine in the fruit fly Drosophila and mice and also contribute ...
Cell & Microbiology
Oct 18, 2013
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(Phys.org) —Environmental conditions have a much stronger influence on the mix of microbes living in various parts of your body than does competition between species. Instead of excluding each other, microbes that fiercely ...
Cell & Microbiology
Jul 16, 2013
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For the first time, researchers at the University of North Carolina at Chapel Hill have isolated adult stem cells from human intestinal tissue.
Cell & Microbiology
Apr 4, 2013
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Without the bacteria that live in our intestines, a drug used against rheumatoid arthritis and inflammatory bowel disease wouldnt work.
Cell & Microbiology
Jun 27, 2012
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