Eleven human genomes in nine days

It's only been three years since UC Santa Cruz researchers proved that long-read human genome assembly using the same nanopore technology developed on campus could be done at all. At the time, it was a monumental effort, ...

How do viruses mutate and jump species?

Viruses are little more than parasitic fragments of RNA or DNA. Despite this, they are astonishingly abundant in number and genetic diversity. We don't know how many virus species there are, but there could be trillions.

Neandertals had older mothers and younger fathers

When the ancestors of modern humans left Africa 50,000 years ago they met the Neandertals. In this encounter, the Neandertal population contributed around two percent of the genome to present day non-African populations. ...

Geneticists zeroing in on genes affecting life span

Scientists believe about 25 percent of the differences in human life span is determined by genetics—with the rest determined by environmental and lifestyle factors. But they don't yet know all the genes that contribute ...

Study advances single-cell transcriptome profiling

With the goal of ensuring that single-cell RNA sequencing makes use of the best possible methods, an international group has benchmarked 13 methods. The group, led by Holger Heyn of the Centro Nacional de Análisis Genómico ...

Capabilities of CRISPR gene editing expanded

Many basic and clinical researchers are testing the potential of a simple and efficient gene editing approach to study and correct disease-causing mutations for conditions ranging from blindness to cancer, but the technology ...

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