Keys to the genome: Unlocking the package with 'pioneer transcription factors'
Scientists at the Montreal Clinical Research Institute have discovered the molecular mechanisms responsible for opening up the human genome and expressing new genes.
Scientists at the Montreal Clinical Research Institute have discovered the molecular mechanisms responsible for opening up the human genome and expressing new genes.
Molecular & Computational biology
Apr 11, 2024
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49
Researchers from Carnegie Mellon University's School of Computer Science have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing ...
Cell & Microbiology
Apr 9, 2024
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The Hare Research Group at the Department of Environmental and Biological Sciences, University of Eastern Finland, has published a chromosomally assembled reference genome for the European brown hare. Reference genomes represent ...
Plants & Animals
Mar 20, 2024
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The human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs, while the remaining pair is sex-determining. The haploid human genome occupies a total of just over 3 billion DNA base pairs. The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences.
The haploid human genome contains an estimated 20,000–25,000 protein-coding genes, far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins, while the rest consists of RNA genes, regulatory sequences, introns and (controversially) "junk" DNA.
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