Weaker transcription factors are better when they work together

Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...

Bacterial colonization of the lung also depends on the host genome

The lung is by no means a sterile place, as was assumed for a long time. In fact, it actually harbors a diverse microbial ecosystem. We know from previous studies that changes in the lung microbiome are associated with diseases ...

Researchers find evolutionary support for induced defenses

Graduate student Reese Martin and his doctoral advisor, Ann Tate, assistant professor of biological sciences, used theoretical modeling to identify a potential relationship between genetic pleiotropy and the evolution of ...

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