Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis, which is critical for ...
Plants & Animals
Mar 13, 2023
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7
A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair. According to the research team, their findings ...
Cell & Microbiology
Mar 7, 2023
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25
Collaborating research groups in China have developed a novel technique, called DNA End tailing and sequencing (DEtail-seq), for meiotic DNA double-strand break (DSB) profiling.
Cell & Microbiology
Mar 2, 2023
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4
Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the ...
Cell & Microbiology
Feb 9, 2023
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69
In most higher organisms, including humans, every cell carries two versions of each gene, which are referred to as alleles. Each parent passes on one allele to each offspring. As they are linked together on chromosomes, adjacent ...
Cell & Microbiology
Oct 24, 2022
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136
In the world of biomolecules, none is more iconic, nor more versatile, than DNA. Nature uses the famous double helix to store the blueprints of all living forms, drawing on a four-letter alphabet of nucleotides.
Bio & Medicine
Oct 4, 2022
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48
DNA double-strand breaks are one of the biggest threats to the genome and a driving force of carcinogenesis. Cellular repair mechanisms such as homologous recombination are essential for the maintenance of genome stability ...
Cell & Microbiology
Aug 24, 2022
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10
Many crustaceans, including lobster, crabs, and barnacles, have a cape-like shell protruding from the head that can serve various roles, such as a little cave for storing eggs, or a protective shield to keep gills moist.
Plants & Animals
Aug 1, 2022
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291
Unisexual reproduction lacks meiotic recombination, resulting in the accumulation of deleterious mutations and hindering the creation of genetic diversity. Thus, unisexual taxa are commonly considered an evolutionary dead ...
Evolution
Jul 11, 2022
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26
Testicles of most mammals are cooled in the scrota, and elevated testicular temperatures lead to spermatogenesis failure and male infertility. A research team led by Shosei Yoshida at the National Institute for Basic Biology ...
Cell & Microbiology
May 26, 2022
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26
