The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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2
DNA is the most important carrier of genetic information. Each cell contains approximately two meters of DNA. To ensure that all this genetic material fits into the small cell nucleus, it must be tightly packed. The DNA is, ...
Cell & Microbiology
Dec 4, 2023
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1
The "read–write" mechanism by which cells replicate and use chemical instructions for expressing genes has been uncovered by RIKEN researchers. The quality and quantity of gene expression correlates not only with instructions ...
Cell & Microbiology
Nov 7, 2023
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69
In eukaryotes, genomic DNA, which is a very long double helix containing all the genetic information, wraps around a globular protein called a histone and folds it many times before being contained within the nucleus.
Molecular & Computational biology
Sep 22, 2023
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1
Researchers led by Prof. Gan Haiyun from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) have documented the parental histones inheritance safeguard mechanism, in which parental ...
Cell & Microbiology
Sep 8, 2023
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36
When organisms pass their genes on to future generations, they include more than the code spelled out in DNA. Some also pass along chemical markers that instruct cells how to use that code. The passage of these markers to ...
Plants & Animals
Aug 28, 2023
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13
Chromatin inheritance during cell division involves the replication of DNA and assembly of nucleosomes onto the replicated DNA, because passage of the DNA replication fork disrupts nucleosomes on the DNA. Half of the histones ...
Cell & Microbiology
Aug 25, 2023
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101
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor ...
Cell & Microbiology
May 24, 2023
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137
New research provides insight into how an enzyme that helps regulate aging and other metabolic processes accesses our genetic material to modulate gene expression within the cell. A team led by Penn State researchers have ...
Cell & Microbiology
Apr 14, 2023
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97
Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary ...
Cell & Microbiology
Apr 7, 2023
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