A team of scientists at the Helmholtz Zentrum München shows changes in the immediate environment of DNA after the ovum and sperm fuse to form the zygote. The results suggest why all conceivable somatic cells can develop ...
Cell & Microbiology
Dec 6, 2016
0
51
Scientists at Tokyo Institute of Technology have developed a sensitive fluorescent antibody probe that specifically detects monomethylation of lysine 20 in histone H4 in living cells. This research has future implications ...
Cell & Microbiology
Sep 12, 2016
0
8
Scientists from A*STAR's Genome Institute of Singapore (GIS) have discovered the unique functions of a specific type of histone modification, which may prove crucial in understanding gene regulation and the development of ...
Biotechnology
Jul 11, 2016
0
24
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
Local modifications in histone proteins alter DNA packing density in the cell nucleus to regulate gene activity. They also form the basis of a code in which the significance of a given pattern or motif depends on its broader ...
Biotechnology
Jan 28, 2016
0
5
DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...
Biotechnology
Nov 6, 2015
1
35
Plants are stakeholders in a subtle and complex chemical warfare to secure optimal growth conditions. Although it has been known for decades that plants produce and release chemical substances to fight their neighbors, it ...
Plants & Animals
Nov 6, 2015
0
90
Researchers at the University of Copenhagen have located a previously unknown function in the so-called histones, which allows for an improved understanding of how cells protect and repair DNA damages. This knowledge may ...
Cell & Microbiology
Oct 23, 2015
0
101
Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such "noise" extends lifespan in these organisms. The team published their findings this month in ...
Cell & Microbiology
Jul 30, 2015
0
928
Researchers at the Institute for Research in Biomedicine (IRB Barcelona), Cambridge University and New York University, led by Modesto Orozco, Group Leader at IRB Barcelona, Director of Life Sciences at the Barcelona Supercomputing ...
Biochemistry
Jul 28, 2015
0
24
