Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...
Cell & Microbiology
Oct 24, 2017
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10
A fertilized human egg develops into multiple tissues, organs and about 200 distinct cell types. Each cell type has the same genes, but they are expressed differently during development and in mature cells.
Cell & Microbiology
Aug 30, 2017
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199
Chromatin remodelers—protein machines that pack and unpack chromatin, the tightly wound DNA-protein complex in cell nuclei—are essential and powerful regulators for critical cellular processes, such as replication, recombination ...
Cell & Microbiology
Aug 15, 2017
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216
In the cells of palm trees, humans, and some single-celled microorganisms, DNA gets bent the same way. Now, by studying the 3-D structure of proteins bound to DNA in microbes called Archaea, University of Colorado Boulder ...
Cell & Microbiology
Aug 10, 2017
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32
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...
Biotechnology
Nov 6, 2015
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35
Research on a modified protein around which DNA is wrapped sheds light on how gene regulation is linked to aging and longevity in nematodes, fruit flies and possibly humans.
Cell & Microbiology
Apr 17, 2015
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47
University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which ...
Cell & Microbiology
Feb 10, 2015
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412
The "Goldilocks effect" in fruit fly embryos may be more intricate than previously thought. It's been known that specific proteins, called histones, must exist within a certain range—if there are too few, a fruit fly's ...
Cell & Microbiology
Jun 12, 2014
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0
(Phys.org) —Monozygotic twins look more similar when they are young than later in life. One of the reasons for this is epigenetic change in the form of chemical modifications of the DNA or its packaging proteins. Environmental ...
Biotechnology
Jun 2, 2014
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