Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils. When these spool-like proteins aren't made correctly, ...
Cell & Microbiology
Mar 24, 2013
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Histone proteins are the proteins that package DNA into chromosomes. Every time the cell replicates its DNA it must make large amounts of newly made histones to organize DNA within the nucleus.
Cell & Microbiology
Jan 17, 2013
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Researchers from the UK and Australia have uncovered a new element of the honeybee's genetic makeup, which may help to explain why bees are so sensitive to environmental changes.
Plants & Animals
Dec 11, 2012
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(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In a study published ...
Cell & Microbiology
Aug 31, 2012
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Two opposing teams battle it out to regulate gene expression on the DNA playing field. One, the activators, keeps DNA open to enzymes that transcribe DNA into RNA. Their repressor opponents antagonize that effort by twisting ...
Cell & Microbiology
Aug 26, 2012
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It's widely accepted that molecular mechanisms mediating epigenetics include DNA methylation and histone modifications, but a team from Thomas Jefferson University has evidence to the contrary regarding the role of histone ...
Cell & Microbiology
Aug 23, 2012
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(Phys.org) -- New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types ...
Cell & Microbiology
May 11, 2012
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When stretched out, the genome of a single human cell can reach six feet. To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating units—each unit known ...
Cell & Microbiology
Apr 30, 2012
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In the cell nucleus, DNA wraps around what are called histone proteins, forming regularly spaced spherical bodies called nucleosomes. Thus, large portions of the genetic material are inaccessible to the gene reading machinery. ...
Biochemistry
Mar 7, 2012
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Centromeres are specialised regions of the genome, which can be identified under the microscope as the primary constriction in X-shaped chromosomes. The cell skeleton, which distributes the chromosomes to the two daughter ...
Cell & Microbiology
Nov 3, 2011
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