Deep-learning algorithm aims to accelerate protein engineering

Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...

Researchers discover SARS-CoV-2 inhibitors

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...

Screening for macrocyclic peptides

Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...

Essential oil components can be tested as drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates. ...

Optical vacuum cleaner can manipulate nanoparticles

Scientists at Tomsk Polytechnic University jointly with Russian and international colleagues developed the concept for constructing an "optical vacuum cleaner." Due to its optical properties, it can trap nanoparticles from ...

How to discover new materials quickly

The number of potential new materials that can be assembled from elements in the periodic table is immense—even if researchers were to limit themselves to the 40 to 50 elements that are non-toxic, eco-friendly, and available ...

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