Deep-learning algorithm aims to accelerate protein engineering

Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...

Researchers discover SARS-CoV-2 inhibitors

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...

Screening for macrocyclic peptides

Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...

Essential oil components can be tested as drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates. ...

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