Tissue in trouble calls in reinforcements to restore health

Northwestern University scientists are the first to discover a cellular process used by animals when a tissue is stressed and in molecular trouble from the expression of misfolded and damaged proteins: The tissue at risk ...

Biochemists trap a chaperone machine in action

Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists ...

Weightlessness weighs heavy on genes -- a fly's perspective

On Earth all biology is subjected to gravity. Some biological systems require gravity for correct orientation (geotropism: plants grow up, roots grow down). In the absence of gravity even human biology is affected: astronauts ...

Study uncovers how DNA unfolds for transcription

(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would be crammed into ...

Recent advance in detonation theory

A detonation wave is a chemical reaction wave propagating at the velocity of a shock wave along the explosive charge. There is great demand for a detonation model that can accurately simulate the detonation process, which ...

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