Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...
Cell & Microbiology
Jan 22, 2015
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"Protein misfolding" diseases such as cystic fibrosis and Alzheimer's may be seriously exacerbated by the body's own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute ...
Cell & Microbiology
Nov 18, 2014
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(Phys.org) —University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn's disease. ...
Biochemistry
Jul 17, 2014
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Many enzymes work only with a co-trainer, of sorts. Scientists at the Technische Universitaet Muenchen and the Cluster of Excellence Nanosystems Initiative Munich show what this kind of cooperation looks like in detail using ...
Cell & Microbiology
Jun 30, 2014
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After a natural disaster like a big fire, countless helpers work together to get rid of debris, to build temporary shelters and to provide food for people in need. When a cell is exposed to dangerous environmental conditions ...
Cell & Microbiology
Mar 10, 2014
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When an organism is exposed to life-threatening conditions, it sounds the alarm and a cellular emergency program, the heat shock response, is initiated. However, the name "heat shock response" is misleading. In the beginning ...
Cell & Microbiology
Feb 28, 2014
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Venturing into space might be a bold adventure, but it may not be good for your immune system. Now a study by researchers at the University of California, Davis and published Jan. 24 in the journal PLOS ONE shows how growing ...
Plants & Animals
Jan 24, 2014
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In the classical view of evolution, species experience spontaneous genetic mutations that produce various novel traits—some helpful, some detrimental. Nature then selects for those most beneficial, passing them along to ...
Evolution
Dec 12, 2013
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The refractive power of the human eye lens relies on a densely packed mixture of proteins. Special protective proteins ensure that these proteins do not clump together as time passes. When this protective mechanism fails, ...
Biochemistry
Oct 23, 2013
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A Dartmouth-led team has discovered a group of stress-related proteins that explains how plants avoid sunburn in intense light, a finding that one day could help biotechnologists to develop crops that can better cope with ...
Cell & Microbiology
Aug 6, 2013
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