An unprecedented wealth of information has been gathered on SARS-CoV-2 in a very short period. This information is primarily focused on the cellular entry process and mechanism of antibody recognition where mainly protein-protein ...
Cell & Microbiology
May 23, 2022
0
22
Glycosylation is a common post-translational modification (PTM) of proteins and plays a crucial role in many biological processes. Many disease biomarkers are glycosylated proteins.
Biotechnology
Apr 8, 2022
0
8
Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.
Biochemistry
Aug 19, 2021
5
6517
Researchers have identified two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team, spearheaded by researchers at IMBA—Institute of Molecular Biotechnology of the Austrian Academy ...
Cell & Microbiology
Aug 10, 2021
1
6650
Many processes in the body are regulated by the functions of proteins. For example, almost all molecules—such as DNA, proteins, oligosaccharides, and small bioactive molecules—are generated by enzymes. However, changes ...
Biochemistry
Aug 10, 2021
0
311
A new international study has found that the key properties of the spikes of SARS-CoV-2 virus which causes COVID-19 are consistent with those of several laboratory-developed protein spikes, designed to mimic the infectious ...
Molecular & Computational biology
Jul 5, 2021
1
29
A new model that applies artificial intelligence to carbohydrates improves the understanding of the infection process and could help predict which viruses are likely to spread from animals to humans. This is reported in a ...
Evolution
Jun 15, 2021
0
65
In a surprise find, scientists have discovered sugar-coated RNA molecules decorating the surface of cells.
Molecular & Computational biology
May 17, 2021
1
2658
A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. Mateusz Sikora of the Max Planck Institute of Biophysics in Frankfurt, ...
Molecular & Computational biology
Apr 1, 2021
0
253
A research group at the RIKEN Center for Computational Science (R-CCS) has found that glycans—sugar molecules—play an important role in the structural changes that take place when the virus which causes COVID-19 invades ...
Biochemistry
Mar 24, 2021
0
50
