The cells in your body are not all the same. Each of your organs has cells with very different functions. For example, liver cells are top-notch secretors, as their job requires them to make and export many of the proteins ...
Cell & Microbiology
Aug 2, 2022
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6
Gene therapy using CRISPR/Cas9 gene editing is currently in clinical trials around the world for a variety of diseases. A report from Boston Children's Hospital, published June 27 in Nature Communications, warns of a potential, ...
Cell & Microbiology
Jul 6, 2022
1
219
The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
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136
Blood-forming stem cells found in bone marrow are the life-saving component used in bone marrow transplants. However, suitable donors cannot be found in many cases. A new study reveals how the human embryo develops the precursor ...
Cell & Microbiology
Apr 28, 2022
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67
Phage therapy, which uses viruses known as bacteriophages to treat bacterial infections, is a long-standing medical procedure whose mechanisms of action are still poorly understood. Scientists from the Institut Pasteur and ...
Cell & Microbiology
Apr 21, 2022
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9
An emerging type of material called a metal-organic framework (MOF) could help improve the delivery of genetic material for treating disease.
Biochemistry
Apr 11, 2022
0
105
People with congenital stationary night blindness (CSNB) are unable to distinguish objects in dim-light conditions. This impairment presents challenges, especially where artificial lighting is unavailable or when driving ...
Veterinary medicine
Mar 23, 2022
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33
It sounds like a plot for a Cold War thriller—training a gene to infiltrate a cell and reside there, unnoticed, until an external self-destruct signal induces it to destroy its new home.
Molecular & Computational biology
Feb 8, 2022
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10
Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...
Cell & Microbiology
Jan 24, 2022
0
52
The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19. A potential new route ...
Bio & Medicine
Dec 27, 2021
1
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