Twenty years ago, scientists and investors were giddy over the promise of gene therapy to cure a host of deadly diseases. But the tragic death of a young man from an experimental treatment in 1999 nearly ended a scientist's ...
Other
Sep 18, 2019
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4
New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body ...
Bio & Medicine
Sep 9, 2019
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160
If you want to conduct groundbreaking but contentious biological research, go to China. Last year, Chinese scientist He Jiankui announced he had created the world's first gene-edited human babies, shocking the world at a ...
Plants & Animals
Sep 4, 2019
1
33
For the past 20 years, researchers have been trying to perfect the construction of human artificial chromosomes, or HACs for short. In a paper published today in Cell, Penn researchers describe a new way to form an essential ...
Molecular & Computational biology
Jul 25, 2019
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52
The applications of CRISPR based genetic engineering tools range from changing colors in butterfly wings to developing gene therapies that might one day cure or prevent human diseases.
Biotechnology
Jun 26, 2019
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1
A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...
Biochemistry
Jun 13, 2019
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4
A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for ...
Biotechnology
Jun 12, 2019
1
535
Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells. Using a gold nanoparticle instead of an inactivated ...
Materials Science
May 27, 2019
3
193
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
0
83
Viruses are often used as vehicles for delivery in gene therapy because they're engineered not to damage the cell once they get there, but neglecting to consider how the virus will exit the cell could have consequences.
Cell & Microbiology
Apr 5, 2019
0
142
