Related topics: cells · mouse model · virus · genes · cancer cells

Studying cellular deliveries

Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells—potentially a form of cell-to-cell communication.

CRISPR opens door to new type of medicine—'genome surgery'

Within a few years, Jim Johnsen and Delaney Van Riper may be among the first to benefit from CRISPR-Cas9 gene editing, a breakthrough that has already revolutionized biology research and promises to resurrect gene therapy.

This RNA-based technique could make gene therapy more effective

Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, ...

Chinese researchers further develop adenine base editing system

Two research teams from East China Normal University and Sun Yat-Sen University in China have developed and improved the ABE system in mouse and rat strains, which has great implications for human genetic disorders and gene ...

Genome damage from CRISPR/Cas9 gene editing higher than thought

Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies ...

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