Scientists funded by the National Institutes of Health have developed a new way to identify the state and fate of individual stem cells earlier than previously possible. Stem cells are undifferentiated, serving as building ...
Cell & Microbiology
Jan 19, 2017
0
6
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
In a study published in Nature, Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) describe how the interplay between transcription factors and epigenetic modifications of DNA ...
Cell & Microbiology
Dec 16, 2015
2
3
Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such "noise" extends lifespan in these organisms. The team published their findings this month in ...
Cell & Microbiology
Jul 30, 2015
0
928
Scientists at the University of Chicago, Harvard, and China have described the surprising discovery and function of a new DNA modification in insects, worms, and algae.
Biotechnology
May 6, 2015
0
110
Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...
Cell & Microbiology
Feb 25, 2015
4
47
University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which ...
Cell & Microbiology
Feb 10, 2015
1
412
A decade ago, gene expression seemed so straightforward: genes were either switched on or off. Not both. Then in 2006, a blockbuster finding reported that developmentally regulated genes in mouse embryonic stem cells can ...
Cell & Microbiology
Aug 11, 2013
0
0
Although human cells have an estimated 20,000 genes, only a fraction of those are turned on at any given time, depending on the cell's needs—which can change by the minute or hour. To find out what those genes are doing, ...
Biotechnology
Jul 23, 2013
0
0
Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions ...
Cell & Microbiology
May 9, 2013
0
0
