Modified RNA has a direct effect on DNA

An article titled "m6A RNA modification as a new player in R-loop regulation," by the Dynamic Gene Regulation research group led by Arne Klungland at IMB, was published in the January edition of Nature Genetics.

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

New understanding of worm stem cells could lead to human therapies

Research from Oxford University published today in the journal Genome Research has found that a special combination of epigenetic modifications crucial to stem cell growth evolved in animals much earlier than previously appreciated. ...

Researchers find genetic 'dial' can control body size in pigs

Researchers from North Carolina State University have demonstrated a connection between the expression of the HMGA2 gene and body size in pigs. The work further demonstrates the gene's importance in body size regulation across ...

Novel histone modifications couple metabolism to gene activity

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...

First step taken toward epigenetically modified cotton

With prices down and weather patterns unpredictable, these are tough times for America's cotton farmers, but new research led by Z. Jeffrey Chen at The University of Texas at Austin might offer a break for the industry. He ...

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