Within almost every human cell is a nucleus six microns in diameter—about one 300th of a human hair's width—that is filled with roughly three meters of DNA. As the instructions for all cell processes, the DNA must be ...
Biotechnology
Oct 9, 2014
0
0
Moving genetic elements from one location to another in a genome makes for a very dynamic situation in terms of development and disease. An EU project has investigated a special type of micro transposable element and its ...
Biotechnology
Jun 18, 2012
0
0
To sustain life, processes in biological cells have to be strictly controlled both in time and in space. Research workers at the Max Planck Institute for Biophysical Chemistry in Göttingen and Freie Universität Berlin have ...
Cell & Microbiology
May 27, 2013
0
0
Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.
Biochemistry
Feb 14, 2023
0
36
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...
Cell & Microbiology
Dec 22, 2011
0
0
Scientists from A*STAR's Genome Institute of Singapore (GIS) have discovered the unique functions of a specific type of histone modification, which may prove crucial in understanding gene regulation and the development of ...
Biotechnology
Jul 11, 2016
0
24
A team of developmental biologists at the University of Massachusetts Amherst led by Dominique Alfandari, with others at MIT, report in a new paper that they have for the first time described how two transcription factors ...
Cell & Microbiology
Oct 10, 2017
0
2
The sites where transcription factors bind within regulatory DNA fall into six distinct patterns that overlap with the factors' functions, Broad scientists find, helping advance a goal of regulatory genomics.
Cell & Microbiology
Jul 11, 2018
0
7
New York University biologists captured highly transient interactions between transcription factors—proteins that control gene expression—and target genes in the genome and showed that these typically missed interactions ...
Molecular & Computational biology
Mar 2, 2020
0
40
A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Rui Benedito has generated a novel genetic tool, called iSuRe-HadCre, that enables the induction of precise genetic alterations ...
Molecular & Computational biology
Jun 11, 2024
0
1
