New insights into evolution of gene expression

Vertebrate organs organize physiological activities, and the diverse expression patterns of thousands of genes determines organ identities and functions. Because of this, the evolution of gene expression patterns plays a ...

Reconstructing the evolutionary history of detoxifying enzymes

Our body produces lots of enzymes that break down toxic substances. One class of such enzymes are the flavin-containing monooxygenases (FMOs), which are present in all tetrapods. Humans have five different FMO genes, of which ...

The molecular evolution of the aconitase superfamily

The aconitase superfamily currently contains four functional enzymes including the archetypical aconitase (referred to as "other aconitase enzymes"), and one hypothetical aconitase X (AcnX). The aconitase enzymes catalyze ...

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