For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects ...
Biochemistry
Jun 13, 2018
0
24
Many pharmaceuticals work by targeting what are known as 'G-protein-coupled receptors.' In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used ...
Biochemistry
Jun 24, 2020
0
44
A research team led by Professor Byung-Chang Suh has investigated the real-time effect of the G-protein cycle, which acts as a switch in the body, on the structural changes in G protein-coupled receptors (GPCRs). Their study ...
Molecular & Computational biology
Mar 31, 2023
0
141
Researchers from Boston University School of Medicine (BUSM) have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases ...
Biotechnology
Jul 6, 2020
0
40
For sugar to taste sweet and for coffee to be stimulating, or even for light to be seen, first they all need to land on a G protein-coupled receptor. Ubiquitous and diverse, these receptors are a cell's chemical detection ...
Biochemistry
Oct 7, 2019
0
27
Researchers at the Paul Scherrer Institute (PSI) have elucidated an important part of a signal pathway that transmits information through the cell membrane into the interior of a cell.
Cell & Microbiology
Apr 25, 2019
0
18
Human cells sense and communicate via cell surface receptors. Information about the environment is relayed to the inside of the cell through dynamic changes in their arrangement or conformation. To gain better understanding ...
Plants & Animals
Jun 23, 2020
0
3
Researchers from Heidelberg University and Sendai University in Japan have used new biotechnological methods to study how human cells react to and further process external signals. They focused on the interaction between ...
Cell & Microbiology
Jul 1, 2019
0
0
Researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, have identified how a protein receptor targeted by about 33% of all federally approved medication works. ...
Biochemistry
Dec 5, 2022
0
103
A new optogenetic tool, a protein that can be controlled by light, has been characterized by researchers at Ruhr-Universität Bochum (RUB). They used an opsin—a protein that occurs in the brain and eyes—from zebrafish ...
Biotechnology
Jul 23, 2021
0
376
