About 30 percent of the proteins encoded by the human genome are membrane proteins—proteins that span the cell membrane so they can facilitate communication between cells and their environment. These molecules are critical ...
Biochemistry
Aug 28, 2018
0
110
Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs). ...
General Physics
May 10, 2013
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0
A new study in the Journal of General Physiology (JGP) shows that the contribution of odorant receptors (ORs) to olfactory response in mammals is much more complex than previously thought, with important consequences for ...
Plants & Animals
Oct 25, 2010
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1
In animals, releasing eggs in a timely manner is vital to maximize the chances of successful fertilization.
Molecular & Computational biology
Mar 3, 2020
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123
G protein-coupled receptors (GPCRs) play essential roles in cell signal transduction and serve as important therapeutic targets for a large number of diseases. Upon binding to extracellular agonists, GPCRs stimulate various ...
Cell & Microbiology
Mar 19, 2020
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127
Exploring how a hazardous fungal pathogen 'tastes' its surroundings within a wheat plant to coordinate virulence could be the key to developing new control strategies, scientists believe.
Biotechnology
Apr 24, 2019
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36
In November 2017, a Titan Krios cryo-electron microscope (cryo-EM) was inaugurated at the ESRF, the European Synchrotron, France. Data collected on this cryo-EM features in a Nature publication describing the activation cycle ...
Biochemistry
Oct 31, 2018
0
22
New research shows the same proteins that enable human senses such as smell also allow certain fungi to sense something they can eat.
Biotechnology
Dec 15, 2020
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65
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter ...
Biotechnology
Jun 21, 2024
0
39
There are a number of G protein-coupled receptors in human cells. As an important component of the cell membrane, these proteins are responsible for detecting different stimuli in the surroundings of a cell within the body ...
Biochemistry
Oct 25, 2021
0
117
