(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors (GPCRs). These ...
Cell & Microbiology
Feb 27, 2013
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Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine. These papers, ...
Cell & Microbiology
Jul 12, 2012
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Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
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30
(PhysOrg.com) -- The mechanism by which cells respond to stimuli and trigger hormonal responses, as well as the senses of sight, smell, and taste, has for the first time been brought into focus with the help of high-brightness ...
Biochemistry
Aug 10, 2011
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Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
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109
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational ...
Cell & Microbiology
Aug 1, 2024
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22
New data on signaling proteins, called G proteins, may prove important in fighting diseases such as cardiovascular, neurodegenerative disorders, and cancer. For many decades scientists have puzzled on "How signaling proteins ...
Biochemistry
Sep 21, 2009
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There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. ...
Biochemistry
Dec 4, 2018
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71
As COVID has demonstrated, when pathogens are moving through the population, we adjust, limiting interactions, even isolating, and generally changing the way we associate with one other. Humans are not alone. New research ...
Evolution
Mar 6, 2023
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36
Cholecystokinin (CCK) and gastrin are the earliest discovered gastrointestinal hormones. They are the most abundant peptides in gastrointestinal tract and central nervous system, acting as physiologically important hormones ...
Biochemistry
Oct 8, 2021
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