Effective pain relief without the debilitating side effects of traditional opioids is closer to becoming a reality thanks to a study by an all-RIKEN team into the structure and dynamics of a drug-bound opioid receptor.
Biotechnology
Jul 18, 2024
0
99
Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the ...
Biochemistry
Jul 5, 2024
0
17
When a cell spreads out or changes its shape to adapt to its environment, the transport rate of proteins between the nucleus and cytoplasm changes. Previously, scientists assumed this change was caused by a shift in the size ...
Cell & Microbiology
Jun 20, 2024
0
39
Drought stress poses a significant challenge to plant survival, affecting growth and productivity. Transcription factors, particularly NAC proteins, play vital roles in plant responses to abiotic stress.
Molecular & Computational biology
Jun 17, 2024
0
13
A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.
Analytical Chemistry
Jun 7, 2024
0
0
AlphaFold 3, unveiled to the world on May 9, is the latest version of an algorithm designed to predict the structures of proteins—vital molecules used by all life—from the "instruction code" in their building blocks.
Biotechnology
May 13, 2024
0
3
Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes that grant them their function.
Bio & Medicine
May 10, 2024
0
216
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function ...
Cell & Microbiology
Apr 10, 2024
0
124
University of Michigan researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Cell & Microbiology
Apr 8, 2024
0
44
Researchers studying the role of proteins in health and disease use experimental tools that inactivate proteins, destroy them, or prevent them from being made in cells. In one approach, they mark targeted proteins with "destroy ...
Biotechnology
Mar 15, 2024
1
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