(Phys.org) —JILA researchers have engineered a short, flexible, reusable probe for the atomic force microscope (AFM) that enables state-of-the-art precision and stability in picoscale force measurements. Shorter, softer ...
Nanophysics
Apr 9, 2014
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Proteins are widely used in medicine, biology and chemistry. Enhancing their inherent properties by adding functional molecules to their structures is a common and important step in many fields. For example, adding fluorescent ...
Biochemistry
Feb 13, 2020
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Researchers at the IBB-UAB have developed the most comprehensive database available to date to help understand the basis of protein aggregation, a phenomenon associated with aging and several pathologies. The new resource, ...
Molecular & Computational biology
Nov 3, 2023
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When Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen. As he describes these molecules, it might be easy to miss the fact that he ...
Molecular & Computational biology
Feb 27, 2019
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Proteins must fold in a specific way to function. This is often assisted by molecular chaperones—small proteins whose job is to help others fold to the right shape. Now, Japanese researchers have discovered that for one ...
Biochemistry
Jul 11, 2018
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The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which ...
Cell & Microbiology
Jun 25, 2024
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Proteins are the workers, messengers, managers, and directors of nearly all inter- and intra-cellular functions in our body. So, all advances in biology, pharmaceuticals, and related fields hinge on having a fundamental understanding ...
Molecular & Computational biology
Oct 4, 2021
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A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
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Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved molecular chaperones. They play an essential role in maintaining protein homeostasis, including facilitating protein folding and degradation, preventing ...
Biochemistry
Jul 27, 2020
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Proteins do most of the work inside the human body, supporting the structure, function, regulation, and repair of organs, tissues and cells. Proteins are synthesized as extended chains of amino acids that must fold into intricate ...
Cell & Microbiology
Feb 23, 2017
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