M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for their bactericidal and tumoricidal ...
Biochemistry
Mar 28, 2023
0
52
Life depends on remarkable arrays of biochemical reactions. Understanding the workings of biomolecules involves real-time monitoring of these reactions. Happening in only tiny fractions of a millisecond, this is very difficult ...
Nanomaterials
Jun 18, 2020
0
5
Despite remarkable medical advances over the last years, cystic fibrosis remains the most prevalent lethal genetic disease. It is due to mutations in the CFTR protein which is normally required to maintain proper fluid balances ...
Biochemistry
Aug 3, 2021
0
359
Extremely intense X-ray pulses can determine the positions of some hydrogen atoms in organic molecules that form small crystals, an all-RIKEN team has shown. Many areas, including drug discovery and materials research, stand ...
Analytical Chemistry
Jun 19, 2023
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15
What do ballet and cell biology have in common? Perhaps more than you might think.
Cell & Microbiology
Apr 2, 2018
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19
Scientists are reporting discovery of a way to help proteins such as the new generation of protein-based drugs -- sometimes heralded as tomorrow's potential "miracle cures" -- get past the biochemical "Entrance Forbidden" ...
Biochemistry
Jul 14, 2010
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0
Scientists who study RNA have faced a formidable roadblock: trying to examine RNA's movements in a living cell when they can't see the RNA. Now, a new technology has given scientists the first look ever at RNA in a live ...
Cell & Microbiology
Oct 22, 2009
0
0
Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...
Cell & Microbiology
Mar 13, 2023
0
3
Researchers in Carnegie Mellon University's Department of Chemistry have developed a nucleic-acid-based photocatalyst that can precisely control atom transfer radical polymerization (ATRP), a popular method used to generate ...
Biochemistry
May 22, 2024
0
62
In a finding that has important ramifications for neurodegenerative disorders such as Alzheimer's disease, RIKEN researchers have discovered how three chaperone molecules in yeast cells work together to break up beta-sheet-rich ...
Biochemistry
May 26, 2022
0
91
