Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case protein subunits ...
Biotechnology
Mar 1, 2012
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Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Cell & Microbiology
Feb 23, 2011
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Transcription is the process of synthesizing messenger RNA by RNA polymerase based on the DNA sequence of a gene and is the initial step in gene expression. In bacteria, σ factor is a key component of RNA polymerase for ...
Biotechnology
May 20, 2019
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Genes contain all the information needed for the functioning of cells, tissues and organs. Gene expression, meaning when and how the genes are read and executed, is thoroughly regulated like an assembly line with several ...
Cell & Microbiology
Jan 9, 2019
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Before DNA can be transcribed into RNA, an early step in turning the genetic template into protein, the nucleus must first assemble a molecular machine called the pre-initiation complex (PIC), capable of unzipping the double ...
Cell & Microbiology
Dec 2, 2014
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For 10 years, Patrick Cramer and his colleagues at Ludwig-Maximilians-Universitaet (LMU) in Munich have probed the structure of RNA polymerase I, a crucial cog in the machinery of all cells. Now they unveil the full three-dimensional ...
Cell & Microbiology
Oct 24, 2013
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DNA is a blueprint for cells to make proteins that allow those cells to function properly. To create the proteins, enzymes copy genetic codes from DNA strands and then transfer the instructions onto RNA in a process called ...
Biotechnology
Apr 24, 2018
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