An team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has determined the three-dimensional structure of the transcription initiation complex, the key intermediate in the process by which cells ...
Cell & Microbiology
Oct 18, 2012
0
0
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
0
65
Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence ...
Molecular & Computational biology
May 4, 2022
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39
Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells—a finding that could be used to control the composition of the gut microbiome, which is important for human health.
Biotechnology
Nov 18, 2020
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24
Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.
Cell & Microbiology
Jan 8, 2019
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100
Gene transcription is the process by which DNA is copied and synthesized as messenger RNA (mRNA)—which delivers its genetic blueprints to the cell's protein-making machinery.
Cell & Microbiology
May 26, 2016
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8
An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of California at Berkeley and ...
Biotechnology
May 11, 2016
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861
A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins ...
Cell & Microbiology
Mar 3, 2016
0
15
(Phys.org) —In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. ...
Biochemistry
Apr 9, 2013
2
0
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase molecule. ...
Biotechnology
May 21, 2012
0
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