p38α protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions. Since the discovery of p38α, various ...
Cell & Microbiology
Dec 19, 2023
0
1
Antibiotic-resistant "superbugs" that can defeat efforts to kill them are an urgent public health crisis, and according to the Centers for Disease Control, more than 2.8 million antibiotic-resistant infections occur each ...
Biochemistry
Dec 18, 2023
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75
A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University ...
Biotechnology
Dec 18, 2023
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85
Scientists at the Indian Institute of Science (IISc) have developed a novel technique to encapsulate liquid droplets used for various applications, including single crystal growth and cell culture.
Materials Science
Dec 14, 2023
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1
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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57
A highly active catalyst capable of synthesizing drug molecules within the body has been developed by RIKEN chemists. In mice, an anticancer drug assembled near tumors using the injected catalyst suppressed tumor growth.
Biochemistry
Dec 8, 2023
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67
When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn't know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a ...
Analytical Chemistry
Dec 8, 2023
0
20
The Chirik Group at the Princeton Department of Chemistry is chipping away at one of the great challenges of metal-catalyzed C–H functionalization with a new method that uses a cobalt catalyst to differentiate between bonds ...
Analytical Chemistry
Dec 7, 2023
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14
People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
0
20
A research team from the University of Vienna, in collaboration with the Constructor University in Bremen, showed that polyoxometalates (POMs) can transport biologically relevant cargo through biological membranes. The study ...
Biochemistry
Dec 5, 2023
0
58
