Most people carry the fungus Candida albicans on their bodies without it causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat. Few antimicrobials are effective, and drug ...
Cell & Microbiology
May 25, 2022
0
105
Creating new chemical compounds, such as new drugs, is not as simple as assembling one of those models with colored balls and sticks you might have seen in a beginning chemistry class. No, it's often a complex process with ...
Analytical Chemistry
May 25, 2022
0
173
A potential cornucopia of neuroactive compounds, which might yield clues to the design of future psychiatric and neurological drugs, has become more accessible to synthetic chemists, thanks to new work from Scripps Research.
Biochemistry
Mar 17, 2022
0
81
The discovery and development of new small-molecule compounds for therapeutic use involves a huge investment of time, effort and resources. Giving a new spin to conventional chemical synthesis, a team of researchers from ...
Other
Jun 1, 2021
0
15
Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.
Biochemistry
Aug 13, 2020
0
179
A new technique in chemistry could pave the way for producing uniform nanoparticles for use in drug delivery systems.
Nanomaterials
Nov 27, 2019
1
58
Organosulfur compounds are widely present in our bodies and the natural environment. They are found in onions, shallots and even cauliflower. Medical research finds that when consumed, they can protect against cancer, heart ...
Materials Science
Nov 21, 2019
0
15
A new web tool speeds the discovery of drugs to kill Gram-negative bacteria, which are responsible for the overwhelming majority of antibiotic-resistant infections and deaths. The tool also offers insights into discrete chemical ...
Cell & Microbiology
Nov 18, 2019
1
233
It's a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a "landmark in drug discovery" with the total synthesis of halichondrin. Known to be a potent anti-cancer agent in ...
Biochemistry
Jun 17, 2019
1
608
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult ...
Biochemistry
Jun 11, 2019
0
3
