Cells are incredibly adept at creating complex molecules, like therapeutics, and can do so much better than many of our best factories.
Biochemistry
Jun 6, 2019
0
131
After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex 'anti-tumour antibiotic' known to be highly effective against cancer cells as well as drug-resistant bacteria, and have ...
Biochemistry
Apr 24, 2019
0
258
The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical ...
Biochemistry
Mar 5, 2019
0
24
With its vast numbers of different lifeforms, the sea is a largely unexplored source of natural products that could be starting points for new pharmaceuticals, such as the antitumor drugs trabectedin and lurbinectedin. Because ...
Materials Science
Feb 19, 2019
0
40
A Purdue-affiliated company is developing a way to reduce drug development costs by more accurately and efficiently modeling molecules and chemical reactions in liquid solutions. This will allow chemists to better understand ...
Materials Science
Apr 6, 2018
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5
The preparation of chiral compounds as intermediates in drug synthesis is one of the most important targets in synthetic organic chemistry. Japanese scientists have now shown that the autocatalytic preparation of a chiral ...
Materials Science
Oct 19, 2016
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8
Scientists from ITMO University and Trinity College have designed an optically active nanosized supercrystal whose novel architecture can separate organic molecules, thus considerably facilitating the technology of drug synthesis. ...
Nanophysics
May 24, 2016
0
11
The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.
Biochemistry
May 23, 2016
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36
A team led by Rice University synthetic organic chemist K.C. Nicolaou has developed a new process for the synthesis of a series of potent anti-cancer agents originally found in bacteria.
Biochemistry
Mar 10, 2016
1
82
Aryl alkyl ethers are important structural motifs found in many biologically active compounds. Therefore, stereoselective etherification is a highly important synthetic operation in the preparation of drug candidates. However, ...
Biochemistry
Sep 15, 2015
0
20
