Researchers compare controlled release of bisphosphonates

Bisphosphonate (BP) drugs are a common treatment strategy to combat calcium-related metabolic disorders, osteoporosis being the most widely known one. These drugs offer several benefits but are plagued by side-effects. One ...

Breakthrough in β-lactam synthesis using nickel catalysts

Led by Director Chang Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a significant advancement in the synthesis of β-lactam scaffolds, ...

New targeting opportunities discovered against canine distemper virus

The highly contagious canine distemper virus is dangerous to dogs and wild life animals. It is also closely related to the equally highly contagious measles virus. Researchers at the University of Bern and the Zurich University ...

This one-atom chemical reaction could transform drug discovery

Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production. Now, in a study recently published in Science, researchers ...

Chemists achieve 'molecular editing' feat

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly ...

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