Evolving strains of multi-drug resistant pathogens are a growing global concern, outpacing drug discovery efforts and undermining the efficacy of existing antibiotics. The development of comprehensive diagnostics for clinical ...
A Brock University research team has created a microscopic robot that has the potential to identify drug resistance to tuberculosis faster than conventional tests.
Evolutionarily conserved transport proteins, such as those belonging to the multidrug and toxic compound extrusion (MATE) superfamily, protect cells against toxic chemicals and contribute to multidrug resistance in cancer ...
MSU-based biologists have reported new understanding of fungal drug resistance mechanisms. To study them, the scientists used baker's yeast expressing fluorescent proteins fused with the membrane transporters. Fungi activate ...
With antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. EMBL researchers have adapted an existing technique to study the melting behaviour of proteins so that it can ...
The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives. Depending on the bacterial species, some combinations stop antibiotics from working to their ...
About half of all drugs, ranging from morphine to penicillin, come from compounds that are from—or have been derived from—nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.
Given the ever-increasing threat of antibiotic resistance, European researchers have developed a method to rapidly test new antibiotic candidates for their potential to be hit by emerging resistance. The high-throughput mutagenesis ...
Through computer simulations, scientists can predict if bacteria can be stopped with popular antibacterial therapies or not – a breakthrough which will help select and develop effective treatments for bacterial infections.
Researchers from North Carolina State University have synthesized an analog of lipoxazolidinone A, a small molecule that is effective against drug-resistant bacteria such as MRSA. This molecule, a new synthetic compound inspired ...
Jul 31, 2018
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