A nanosized polymer, developed by a research team from Ben-Gurion University of the Negev, can selectively deliver chemotherapeutic drugs to blood vessels that feed tumors and metastases and has emerged as an effective treatment ...
Bio & Medicine
Apr 8, 2024
0
72
Vanderbilt biochemists are part of a team taking a stride toward the development of antibacterials to treat uncomplicated urinary tract infections, a pervasive bacterial infection that affects 50%–60% of women in their ...
Biochemistry
Mar 28, 2024
0
78
Cystic fibrosis is the most common, life-limiting genetic condition in Australia. It affects the lungs, digestive system, and reproductive system, producing excess mucus, infections, and blockages.
Bio & Medicine
Mar 27, 2024
0
2
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. ...
Bio & Medicine
Mar 14, 2024
0
17
Given the worldwide prevalence of drug-resistant bacteria, the research community is on the lookout for alternative bactericidal treatment approaches. In a recent study, Japanese researchers have now compared bacteriophage-derived ...
Cell & Microbiology
Mar 12, 2024
0
2
Antimicrobial resistance is a story of constantly moving parts and players. With every new or tweaked antibiotic or antimicrobial drug, the targeted pathogens begin the evolutionary dance of acquiring resistance, prompting ...
Cell & Microbiology
Mar 7, 2024
0
5
Vanderbilt scientist Houra Merrikh led a team of researchers who discovered the first anti-evolution chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform ...
Biochemistry
Feb 29, 2024
0
15
Scientists at the University of Illinois Chicago and Harvard University have developed an antibiotic that could give medicine a new weapon to fight drug-resistant bacteria and the diseases they cause.
Cell & Microbiology
Feb 17, 2024
0
121
Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
0
8
For the first time, researchers have analyzed the impact of antibiotic use on the rise of treatment-resistant bacteria over the last 20 years in the UK and Norway. They show that while the increase in drug use has amplified ...
Cell & Microbiology
Jan 11, 2024
0
46
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
This text uses material from Wikipedia, licensed under CC BY-SA
