New ligand-guided technique enhances drug development

Achieving a level of precision to create complex medicines and materials with extreme accuracy is a longstanding goal of scientists and pharmaceutical companies. If achieved, that precision could lead to the development of ...

A catalyst for electronically controlled C–H functionalization

The Chirik Group at the Princeton Department of Chemistry is chipping away at one of the great challenges of metal-catalyzed C–H functionalization with a new method that uses a cobalt catalyst to differentiate between bonds ...

Computational model helps with diabetes drug design

For diabetes patients who must give themselves frequent insulin injections, the risk of low blood sugar can be life-threatening. A potential solution is a type of engineered insulin that circulates in the body and springs ...

New stapling method solves floppy peptide problem

In a cutting-edge discovery, published in the Journal of the American Chemical Society, Florey scientists have solved a long-standing problem: the need for an affordable, simple way to make peptide-based drugs that hold their ...

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