Quantum mechanics could explain why DNA can spontaneously mutate

The molecules of life, DNA, replicate with astounding precision, yet this process is not immune to mistakes and can lead to mutations. Using sophisticated computer modeling, a team of physicists and chemists at the University ...

Chemists discover new reactivity of strained molecules

In synthetic organic chemistry, so-called cycloadditions are a particularly important class of reactions. With this type of reaction, ring-shaped molecules can be constructed simply and efficiently by joining ("adding") two ...

Chemical reaction design goes virtual

Researchers at the Institute for Chemical Reaction Design and Discovery and Hokkaido University have developed a virtual ligand-assisted (VLA) screening method that could drastically reduce the amount of trial and error required ...

Biosynthesis pathway of a new DNA nucleobase elucidated

DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. ...

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