One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. ...
Molecular & Computational biology
Jul 1, 2022
0
100
DNA methylation is a major epigenetic modification that is crucial for mammalian development. For instance, DNA methylation is central to inexhaustible biological processes, such as gene regulation and cell fate decisions. ...
Cell & Microbiology
Apr 18, 2022
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24
Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.
Molecular & Computational biology
Feb 28, 2022
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1748
Genetic information is stored in DNA as a sequence of specific base pairings. This is passed on largely unchanged from one generation to the next. But how is it possible that cells differ so massively in form and function, ...
Evolution
Feb 10, 2022
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4
For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, ...
Molecular & Computational biology
Feb 3, 2022
0
159
Growing up is a complex process for multi-celled organisms—plants included. In the days or weeks it takes to go from a seed to a sprout to a full plant, plants express hundreds of genes in different places at different ...
Plants & Animals
Jan 12, 2022
0
32
What determines how a cell's genome is regulated to ensure proper growth and development? Turns out, the parts of the genome that are turned on or off in each cell-type or tissue play a major role in this process. Now, a ...
Biotechnology
Jan 11, 2022
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41
Mammalian offspring inherit two versions, or alleles, of each gene, with one allele from each biological parent. However, gene expression is tightly regulated and certain genes undergo the phenomenon of "genomic imprinting," ...
Molecular & Computational biology
Jan 4, 2022
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118
Researchers have shown for the first time that embryonic cells destined to become either egg or sperm rely on different methods of repressive gene regulation.
Cell & Microbiology
Dec 9, 2021
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39
Chemical modifications of histones, the small proteins around which DNA is wrapped, are known to affect gene expression. In a study conducted in C. elegans, researchers from the Gasser group show that the defining modification ...
Cell & Microbiology
Nov 15, 2021
0
53
