Researchers at the Center for Genome Engineering, within the Institute for Basic Science (IBS, South Korea) have identified the mistake rate of DNA editing tools known as adenine base editors, which are based on CRISPR. Assessing ...
Biotechnology
Mar 5, 2019
0
17
The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...
Bio & Medicine
Feb 27, 2019
2
53
Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have combined their knowledge of bacterial genetics and web search algorithms to build a DNA search engine for microbial data. The search engine, described ...
Biotechnology
Feb 4, 2019
0
80
How do you make yeast work harder? Not to make bread, but in processes that yield chemicals and pharmaceuticals. Industries currently use a yeast called Saccharomyces cerevisiae. They'd like it to work better. The answer ...
Biotechnology
Jan 14, 2019
0
21
A new study published in the Metabolic Engineering Journal describes a method based on CRISPR/Cas9, which enables flexible engineering of essential and nonessential enzymes without additional engineering. This has multiple ...
Biotechnology
Aug 22, 2018
0
5
What drives cells to live and engines to move? It all comes down to a quantity that scientists call "free energy," essentially the energy that can be extracted from any system to perform useful work. Without this available ...
General Physics
Jun 8, 2018
0
131
Rice University researchers have developed a computational model to quantify the mechanism by which CRISPR-Cas9 proteins find their genome-editing targets.
Biotechnology
Oct 17, 2017
0
13
Biochemical engineers at Johns Hopkins University used sequences of DNA molecules to cause water-based gels to change shape, demonstrating a new tactic to produce soft robots and "smart" medical devices that don't rely on ...
Materials Science
Sep 18, 2017
0
18
Discovering the function of a gene requires cloning a DNA sequence and expressing it. Until now, this was performed on a one-gene-at-a-time basis, causing a bottleneck. Scientists at Rutgers University-New Brunswick in collaboration ...
Biotechnology
Jun 26, 2017
0
37
Scientists at the Center for Genome Engineering, within the Institute for Basic Science (IBS), in collaboration with KIM Eunji (ToolGen Inc.) and KIM Jeong Hun (Seoul National University) have engineered the smallest CRISPR-Cas9 ...
Biotechnology
Feb 21, 2017
0
11
