Method identifies mutations that drive genetic diseases

(PhysOrg.com) -- For the first time, a new computational method allows researchers to identify which specific molecular mechanisms are altered by genetic mutations in proteins that lead to disease. And they can apply this ...

How cells' sensing hairs are made

(PhysOrg.com) -- Body cells detect signals that control their behavior through tiny hairs on the cell surface called cilia. Serious diseases and disorders can result when these cilia do not work properly. New research from ...

Cancer is a p53 protein aggregation disease

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB, ...

Worm research defines the role of multiple disease genes in cilia

(PhysOrg.com) -- University College Dublin researchers led by Conway Fellow, Dr Oliver Blacque have outlined how cilia disease gene products regulate important aspects of early cilium formation and the integrity of the ciliary ...

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