First successful total synthesis of Erythropoietin

(Phys.org)—"Blood is quite a peculiar kind of juice"—that is what Mephisto knew, according to Goethe's "Faust". But if blood really is very special, then erythropoietin (EPO) must be a very special molecule, as it triggers ...

How rocket science may improve kidney dialysis

A team of researchers in the United Kingdom has found a way to redesign an artificial connection between an artery and vein, known as an Arterio-Venous Fistulae, which surgeons form in the arms of people with end-stage renal ...

Taking steps toward a wearable artificial kidney

There just aren't enough kidney transplants available for the millions of people with renal failure. Aside from a transplant, the only alternative for patients is to undergo regular dialysis sessions to clear harmful cellular ...

Crowdsourcing breakthrough treatments for blood infections

If asked how today's toughest medical problems are being solved, most people would probably envision highly skilled physicians and scientists working countless hours with sophisticated lab equipment, not people sitting in ...

Key find for treating wastewater on World Water Day

A newly developed membrane used to separate waste from water could become key in the treatment of pollutants ranging from acid mine drainage to oil-containing wastewater, as well as in processes ranging from desalination ...

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Dialysis

In medicine, dialysis (from Greek "dialusis", meaning dissolution, "dia", meaning through, and "lusis", meaning loosening) is primarily used to provide an artificial replacement for lost kidney function (renal replacement therapy) due to renal failure. Dialysis may be used for very sick patients who have suddenly but temporarily, lost their kidney function (acute renal failure) or for quite stable patients who have permanently lost their kidney function (stage 5 chronic kidney disease). When healthy, the kidneys maintain the body's internal equilibrium of water and minerals (sodium, potassium, chloride, calcium, phosphorus, magnesium, sulfate) and the kidneys remove from the blood the daily metabolic load of fixed hydrogen ions. The kidneys also function as a part of the endocrine system producing erythropoietin and 1,25-dihydroxycholecalciferol (calcitriol). Dialysis is an imperfect treatment to replace kidney function because it does not correct the endocrine functions of the kidney. Dialysis treatments replace some of these functions through diffusion (waste removal) and ultrafiltration (fluid removal).

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